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Is Schizophrenia genetic?

I was diagnosed with a mental health disorder called paranoid Schizophrenia in 2018, and I was not aware of any genetic reasons, until my mother mentioned that my uncle has schizophrenia, and it runs in the family.

An interesting question we may ask is if Schizophrenia is caused by genetics (hereditary) so is it passed down through genetics and do people genetically inherent it?

Schizophrenia is linked to a brain disease which some research suggest the disease is caused by imbalance of dopamine and serotine and others have found a change in the body’s sensitivity to the neurotransmitters is part of the cause of schizophrenia.

This gives us another question is genetic component causing a brain disease which results in chemical imbalance of dopamine and serotine?

Another question we may ask is if it is a brain diseased linked to genetics then which genes are reasonable for that. Here is snippet of info from “Deletions or duplications of genetic material in any of several chromosomes, which can affect multiple genes, are also thought to increase schizophrenia risk. In particular, a small deletion (microdeletion) in a region of chromosome 22 called 22q11 may be involved in a small percentage of cases of schizophrenia.”

The key words here are may so it’s not certain, and small which also is important to understand the impact of genetics as a cause of Schizophrenia.

Common questions related to genetics and schizophrenia are, trying to understand if there is a link between genes and schizophrenia, is the genetic component really causing schizophrenia, and some people have genetic predisposition to get schizophrenia,

Another related question is if schizophrenia is caused by a gene mutation and here is some info on this “Scientists at The Feinstein Institutes for Medical Research, in collaboration with Columbia University, say they have identified a gene mutation that could result in schizophrenia, a chronic brain disorder”.

What they don’t say is whether it is rare or common and they use the word could so it’s not certain.

To give you some answers, yes, there is research showing that there is a link between genetics and schizophrenia, and some people may have inherited it through genes, and some may have a gene mutation that caused schizophrenia.

The most important research related to a link between genes and schizophrenia is research on twins. In one book I’ve read probability of being identified with Schizophrenia is twins is 50% so quite a lot, and another statistics says a child of a parent who has schizophrenia is 10% so in my case my child Jasper has 10% chances of getting Schizophrenia due to genes.

Another book (Author Paul Miller) gives a clear answer to how many people are affected by genes, and it says “… 22.4% to 30% may have genetic causation, whereas 70% to 78% of schizophrenia’s causation is, therefore, nongenetic”. Of course the key word in this statement is may, so it is not certain, although probability of it might be quite high, as it’s quite easy to get reliable statistics on twins, but as much as twins grow up in similar environments, that is not to say that the same environment is not causing it.

So does genetics play a role in schizophrenia? It seems it does, but only to a certain degree, and it is more visible, in twins, less when passed by parents but still high, and less in other cases, like an uncle.

In my case my uncle (Mother’s brother) has Schizophrenia so it’s difficult to work out if it caused my episodes, or maybe contributed to it, or maybe it was this genetic component that triggered an episode, but with today’s technology and research there is no way to verify that, we can just guess, however I do know that my significant reason for my Schizophrenia was trauma, and relapse of trauma that caused me second severe episode of schizophrenia which is considered environmental reason, and it seems it’s much more common than most people think, although the good thing is that if it is caused by trauma, then trauma itself can be effectively treated which I have done, and it did significantly reduced my symptoms almost to nothing, but I still continue with the therapy just to be safe and reduce risks of third episode, as there is a chance I still have chemical imbalance in the brain, and there still might be a genetic component which may trigger third episode that I would like to avoid at all cost.

We didn’t discussed environment much but based on the statistics above we can assume that environment may be responsible for up to 78% of cases, and based on my knowledge and research related to trauma and emotional problems, emotional issues seems to be closely linked to symptoms of Schizophrenia (I had a lot before an episode), and it’s likely trauma is a significant environmental factor that may cause Schizophrenia.

What we don’t understand well is if we treated trauma before an episode of Schizophrenia, would number of genetic causes drop? I personally feel that there would be an impact as I believe genetics will vary in “power” in some cases it may significantly contribute to schizophrenia and others may be just a final push to break someone’s mind.

My main insight from this article is this… You currently can’t control genetics, but if trauma is significant factor that is something we can resolve through effective therapy (like EFT / Havening Techniques / EMDR etc. which often in my experience relates to core unhealthy believes and “internal” conflicts of personality, values, needs.)

My action is to research more ways effectiveness of therapy to treat Schizophrenia, as I’m a living example that it can achieves amazing results, and I don’t believe I’m an exception, and next figure out if I can someone used my experience, knowledge and research and part of my charity (KOKORO Intelligence) figure out if I can help people with Schizophrenia mainly by getting a job as employment rate is <10% and I do believe there is high likelihood that therapy and coaching would be highly effective for unemployed (or part-timers) to get a full-time job (or work more hours on a part-time basis).

Take care


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